Executive Committee
Alistair Nichol
Alistair is the Chair of Critical Care Medicine in University College Dublin (UCD), and the Director of the Irish Critical Care - Clinical Trials Network (ICC-CTN). He is the Dept Director of the Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia. Alistair works clinically in St. Vincent’s University Hospital in Dublin and is an honorary Intensivist in the Alfred Hospital in Melbourne. He has been awarded over 70 million euros in research funding and published numerous articles in the world’s highest impact journals, including first author publications in the NEJM, Lancet and JAMA. Apart from having multiple jobs Alistair also has 4 kids under 14 years of age. He obviously therefore has no hobbies, no sporting interests but he lives in hope of this improving :)
Kathy Brickell
Kathy leads the coordination of our trials portfolio; their implementation and management in the ICU in St. Vincent’s University Hospital in Dublin, and also plays an important role in their set-up across our network. Kathy has worked on over 20 critical care trials to date, champions our PPIE activities and is an experienced trial monitor and outcome assessor. Kathy is chair of the ICC-CTN PPI work package.
With over 20 years’ experience as an ICU nurse, Kathy brings her knowledge and expertise to this role.
Kathy has a passion for scuba diving and the sea. She also loves to travel and maintains a regular yoga practice.
Kate Ainscough
Kate is the ICC-CTN Network Manager and works to support the portfolio of clinical trials, research projects and activities delivered by the Network. Kate has a background in food and nutrition science; studying at UCD and the University of Ulster, Coleraine to undertake her undergraduate degree, masters and PhD. Now working in the critical care research arena, Kate is also collaborating with local and international clinical nutrition colleagues working in critical care to deliver a programme of nutrition research in Ireland. In her spare time, Kate enjoys the company of family, friends and her beloved boxer dogs, reads books on philosophy and pursues interior design interests.
Danny McAuley
Danny McAuley is a Consultant and Professor in Intensive Care Medicine at the Regional Intensive Care Unit at the Royal Victoria Hospital and Queen’s University of Belfast. He undertook his training in Belfast, Birmingham, London and San Francisco. He is Programme Director for the MRC/NIHR Efficacy and Mechanism Evaluation (EME) programme. He has several research interests including Acute Respiratory Distress Syndrome and clinical trials. Danny is Co-Vice-Chair of the ICC-CTN’s Work Package 1 - Optimising Trial Coordination, Performance and Methodology.
Anna Curley
Dr Anna Curley works in the National Maternity Hospital, Dublin. She was previously a neonatal consultant in Cambridge, UK for 11 years and has worked in Ireland, UK, Australia and Africa. She is an Associate Professor in University College Dublin. Whilst working as a neonatologist in Cambridge, Anna also worked in medical regulation for the Medical Council from 2013-2016. Her original research doctorate was based on chronic lung disease in preterm infants and her subspecialty clinical interest is in Neonatal Cardiorespiratory medicine. She has been involved in multiple neonatal randomised controlled trials as Chief Investigator or co-investigator. She was co-chief investigator of PlaNeT-2 study, a platelet transfusion threshold trial which demonstrated increased mortality/major bleeding with the use of higher neonatal platelet transfusion thresholds (NEJM 2018) and is now preparing the PlaNeT-3 study of differing platelet volumes in preterm babies in the UK and Ireland (funded by HRB DIFA). Anna is Vice-Chair of the ICC-CTN’s Work Package 5 - Sustainability, Growth and Global Integration.
Bairbre McNicholas
Dr Bairbre McNicholas is a medical intensivist and nephrologist with basic science training in immunology, having completed a Ph.D. and post-doctoral and nephrology training in Ireland and at the University of Washington, Seattle respectively. She completed a post certificate of specialist training fellowship in Intensive Care Medicine in 2018. She currently practices as a consultant Intensivist and Nephrologist at Galway University Hospital. She is a member of the Irish Critical Care Trials Group Executive Committee, a senior clinical lecturer at University of Galway, School of Medicine and is active in both clinical and translational research. Bairbre is Co-Vice-Chair of the ICC-CTN’s Work Package 3 - Knowledge Exchange and Dissemination.
Clodagh Rock
Ms Clodagh Rock is a former ICU patient and trial participant. Clodagh is a leading member of the ICC-CTN Public and Patient Involvement (PPI) group since its inception (2020). She is co-vice chair of the ICC-CTN PPI work package and ICC-CTN Executive Committee member where she provides essential insights as a former patient and supports and develops the group’s activities and meetings.
Declan Devane
Declan trained as a nurse and a midwife, meandered (with the help of opportunity, interest and luck) his way into trial methodology and evidence synthesis and his work now focusses on a blend across randomised trials and synthesising evidence across a number of clinical areas.
Declan is the Chair in Health Research Methodology and Deputy Dean of the College of Medicine, Nursing and Health Sciences at the University of Galway. He is also the Scientific Director of the HRB-Trials Methodology Research Network, Director of Evidence Synthesis Ireland and Director of Cochrane Ireland. Declan is Co-Vice-Chair of the ICC-CTN’s Work Package 1 - Optimising Trial Coordination, Performance and Methodology.
Gerard Curley
Gerard Curley is Professor of Anaesthesia and Critical Care at the Royal College of Surgeons in Ireland and Consultant in Anaesthesia and Intensive Care in Beaumont Hospital. He completed clinical and research training in Ireland and Toronto, under the supervision of Professor John Laffey and Professor Brian Kavanagh. His translational research focuses on the role of inflammatory pathways, resolution mediators and innate immune dysfunction in the pathogenesis of critical illness. The group’s aim is to develop novel immunomodulatory therapies to promote the resolution of inflammation. Ger is the lead for the ICC-CTN’s Work Package 4 - Clinical Trials / Trialists of the Future.
Kiran Reddy
Kiran Reddy is an early career researcher member of the ICC-CTN executive committee. He is an HRB/Wellcome Trust funded research fellow on the ICAT Programme and a senior clinical trainee in anaesthesia and intensive care medicine on the SAT scheme. He is currently based in the Wellcome-Wolfson Institute for Experimental Medicine at Queen’s University Belfast. Kiran’s research interests focus on using large clinical datasets to elucidate biological subgroups of critical care syndromes, particularly acute respiratory failure, and leveraging these subgroups to develop stratified precision medicine trials in intensive care medicine.
Patrick Mallon
Professor Paddy Mallon is Professor of Microbial Diseases in University College Dublin (UCD) and an Infectious Diseases Specialist at St Vincent’s University Hospital, Dublin. He is the director of the UCD Centre for Experimental Pathogen Host Research (CEPHR), which focuses on translational research into outcomes of infections such as HIV, COVID and tuberculosis. He is the National Coordinator for the EU VACCELERATE network that provides a platform for COVID19 vaccine trials. His own research interests include age-related outcomes in HIV and host biological determinants of outcome from infection. He is on the governing board of the European AIDS Clinical Society, Head of Education for EACS and is a member of the EACS Comorbidities Guidelines Panel.
Jon Silversides
Jon is a Clinical Senior Lecturer in Critical Care at Queen’s University Belfast, and a Consultant in Critical Care and Anaesthesia at the Belfast Health and Social Care Trust. He developed an interest in clinical research while undertaking a fellowship in critical care medicine at the University of Toronto in 2011-12, and completed a part-time PhD at QUB between 2015 and 2019.
Jon’s research is driven by clinical challenges in the ICU and the operating theatre, and includes clinical trials and experimental medicine approaches. His research interests in critical care include the management of fluid therapy and deresuscitation in sepsis and other critical illnesses, including the use of ultrafiltration. Within perioperative medicine, he is chief investigator for the SINFONIA trial, comparing sugammadex with neostigmine for prevention of post-operative pulmonary complications.
Jon leads the critical care specialty group in the Northern Ireland Clinical Research Network, is on the executive committee of the Irish Critical Care Trials Network, and is a Chief Investigator scheme member of the Perioperative Medicine Clinical Trials Network. Jon is Co-Vice-Chair of the ICC-CTN’s Work Package 3 - Knowledge Exchange and Dissemination.
Peter Doran
Prof Peter Doran is Established Professor of Clinical Trials and Director of the Institute for Innovative clinical Trials at the University of Galway. Under his leadership the Institute is focused on delivering better outcomes for patients by building on the depth of academic and clinical expertise at Galway, The research programme tackles the major health issues facing society today and into the future.
Prof. Peter Doran earned his BSc. from Dublin City University in 1998 and his PhD from University College Dublin in 2001. He was the founding Director of the UCD Clinical Research Centre. Under his leadership the UCD CRC developed an internationally renowned clinical research programme.
Prof Doran leads a significant biomarker research programme and has established a high throughput biomarker validation laboratory, which is contributing to major national and international end organ damage biomarker studies, reflecting his research interests in the molecular drivers of organ damage, biomarker discovery and translation to practice.
Prof Doran also has significant research interests in advancing trial conduct through primary methodology research, novel trial designs, research prioritisation and sustainable trials. Prof Doran also has a significant track record in clinical research education having established the graduate taught programme in clinical and translational research which includes a suite of programmes designed to address the career stage specific education and training requirements of clinical research personnel. Peter is Chair of the ICC-CTN’s Work Package 5 - Sustainability, Growth and Global Integration.
Patrick Murray
Patrick Murray is a Full Professor of Clinical Pharmacology in University College Dublin (UCD), and a consultant physician (clinical pharmacologist & nephrologist) at the Mater Misericordiae University Hospital (MMUH), Dublin, Ireland. He received his medical education at UCD. Following his internship at MMUH, he completed a residency in Internal Medicine at Hennepin County Medical Center in Minneapolis, USA. He completed fellowship training programmes in nephrology, critical care medicine, and clinical pharmacology at the University of Chicago Hospitals (UCH), USA. He practiced as an intensivist, nephrologist, and clinical pharmacologist at UCH from 1996–2008, serving as the fellowship training programme director in nephrology, also directing the Acute Dialysis Service. He has a longstanding interest in research and education to improve the prevention, diagnosis, and therapy of acute kidney injury and nephrotoxicity, and the pharmacotherapy of patients with kidney disease. He is a member of several international consensus groups that have produced guidelines for research and practice in the field of acute kidney injury (ADQI, AKIN, KDOQI).
Since 2008, he has been the inaugural Professor of Clinical Pharmacology at UCD, and a Consultant in Nephrology & Clinical Pharmacology at MMUH and at St. Vincent’s University Hospital. He is Chair of the MMUH Drugs & Therapeutics Committee. He is the Clinical Director of the UCD Clinical Research Centre (UCD CRC). In 2012, he was appointed Director of the Dublin Centre for Clinical Research (DCCR) Consortium Network, and also Clinical Director of the Irish Clinical Research Infrastructure Network (ICRIN). From December 2012 through June 2018, he served as the Dean and Head of the School of Medicine at UCD. He is currently Director of the UCD CRC. Pat is Vice-Chair of the ICC-CTN’s Work Package 5 - Sustainability, Growth and Global Integration.